GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:24673808
| Citation |
Tatsuno, I, Isaka, M, Okada, R, Zhang, Y and Hasegawa, T (2014) Relevance of the two-component sensor protein CiaH to acid and oxidative stress responses in Streptococcus pyogenes. BMC Res Notes 7:189 |
|---|---|
| Abstract |
The production of virulence proteins depends on environmental factors, and two-component regulatory systems are involved in sensing these factors. We previously established knockout strains in all suspected two-component regulatory sensor proteins of the emm1 clinical strain of S. pyogenes and examined their relevance to acid stimuli in a natural atmosphere. In the present study, their relevance to acid stimuli was re-examined in an atmosphere containing 5% CO2. |
| Links |
PubMed Online version:10.1186/1756-0500-7-189 |
| Keywords |
|
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000160: phosphorelay signal transduction system |
IMP: Inferred from Mutant Phenotype: |
P |
Figure 4.A-C Shows hydrogen peroxide assays of wild-type spy1236 (CiaH) containing cells as well as cells with deleted spy1236 genes. The assay pertains to the cells ability to withstand oxidative damage using hydrogen peroxide treatments,as it is testing spy1236 role in oxidative stress response. Overall, whenever the cell contained the knockout spy1326 gene, there was a lower survivability. |
complete |
| |||
See also
References
See Help:References for how to manage references in GONUTS.
