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PMID:23572854
| Citation |
Kamberi, LS, Gorani, DR, Hoxha, TF and Zahiti, BF (2013) Aortic Compliance and Stiffness Among Severe Longstanding Hypertensive and Non-hypertensive. Acta Inform Med 21:12-5 |
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| Abstract |
Abnormal aortic function in hypertension is generally attributed to accelerated breakdown of elastin in the aorta, leading to dilatation of the lumen and stiffening of the wall as elastin is replaced with stiffer collagen. Aortic stiffness is an independent predictor of cardiovascular risk and all-cause and cardiovascular mortality. Vascular stiffening can activate endothelium which in turn may promote atherogenesis. Modulation of arterial stiffness has been shown to be successfully managed via changes in lifestyle and put under control of hypertension pharmacologically with antihypertensive drugs and statins. |
| Links |
PubMed Online version:10.5455/AIM.2013.21.12-15 |
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