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PMID:23259795
Citation |
Fan, CW, Chen, CY, Chen, KT, Shen, CR, Kuo, YB, Chen, YS, Chou, YP, Wei, WS and Chan, EC (2012) Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo. J Transl Med 10:254 |
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Abstract |
Membrane-bound phospholipid scramblase 1 (PLSCR1) is involved in both lipid trafficking and cell signaling. Previously, we showed that PLSCR1 is overexpressed in many colorectal carcinomas (CRCs). In the present study, we investigated the tumorigenic role of PLSCR1 in CRC and suggest that it is a potential therapeutic target. |
Links |
PubMed PMC3551821 Online version:10.1186/1479-5876-10-254 |
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Significance
Annotations
Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
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See also
References
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