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PMID:23259795

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Citation

Fan, CW, Chen, CY, Chen, KT, Shen, CR, Kuo, YB, Chen, YS, Chou, YP, Wei, WS and Chan, EC (2012) Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo. J Transl Med 10:254

Abstract

Membrane-bound phospholipid scramblase 1 (PLSCR1) is involved in both lipid trafficking and cell signaling. Previously, we showed that PLSCR1 is overexpressed in many colorectal carcinomas (CRCs). In the present study, we investigated the tumorigenic role of PLSCR1 in CRC and suggest that it is a potential therapeutic target.

Links

PubMed PMC3551821 Online version:10.1186/1479-5876-10-254

Keywords


Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status


See also

References

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