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PMID:23249255
Citation |
Dempwolff, F, Wischhusen, HM, Specht, M and Graumann, PL (2012) The deletion of bacterial dynamin and flotillin genes results in pleiotrophic effects on cell division, cell growth and in cell shape maintenance. BMC Microbiol. 12:298 |
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Abstract |
In eukaryotic cells, dynamin and flotillin are involved in processes such as endocytosis and lipid raft formation, respectively. Dynamin is a GTPase that exerts motor-like activity during the pinching off of vesicles, while flotillins are coiled coil rich membrane proteins with no known enzymatic activity. Bacteria also possess orthologs of both classes of proteins, but their function has been unclear. |
Links |
PubMed PMC3551649 Online version:10.1186/1471-2180-12-298 |
Keywords |
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Significance
Annotations
Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|
GO:0051781: positive regulation of cell division |
ECO:0000315: |
P |
As show in Figure 1, a deletion mutation of the gene encoding EzrA leads to improper partitioning of a cell into its daughter cells |
complete | ||||
involved_in |
GO:0051781: positive regulation of cell division |
ECO:0000315: mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
GO:0090529: cell septum assembly |
ECO:0000315: |
P |
As shown in figure 1, cells with a deletion mutation in the gene for ypbR developed double septa during cytokinesis. |
complete | ||||
involved_in |
GO:0090529: cell septum assembly |
ECO:0000315: mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
See also
References
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