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PMID:23249255

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Citation

Dempwolff, F, Wischhusen, HM, Specht, M and Graumann, PL (2012) The deletion of bacterial dynamin and flotillin genes results in pleiotrophic effects on cell division, cell growth and in cell shape maintenance. BMC Microbiol. 12:298

Abstract

In eukaryotic cells, dynamin and flotillin are involved in processes such as endocytosis and lipid raft formation, respectively. Dynamin is a GTPase that exerts motor-like activity during the pinching off of vesicles, while flotillins are coiled coil rich membrane proteins with no known enzymatic activity. Bacteria also possess orthologs of both classes of proteins, but their function has been unclear.

Links

PubMed PMC3551649 Online version:10.1186/1471-2180-12-298

Keywords


Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

BACSU:EZRA

GO:0051781: positive regulation of cell division

ECO:0000315:

P

As show in Figure 1, a deletion mutation of the gene encoding EzrA leads to improper partitioning of a cell into its daughter cells

complete
CACAO 6808

BACSU:EZRA

involved_in

GO:0051781: positive regulation of cell division

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

BACSU:YPBR

GO:0090529: cell septum assembly

ECO:0000315:

P

As shown in figure 1, cells with a deletion mutation in the gene for ypbR developed double septa during cytokinesis.

complete
CACAO 6807

BACSU:YPBR

involved_in

GO:0090529: cell septum assembly

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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