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PMID:23056489

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Citation

Funken, H, Bartels, KM, Wilhelm, S, Brocker, M, Bott, M, Bains, M, Hancock, RE, Rosenau, F and Jaeger, KE (2012) Specific Association of Lectin LecB with the Surface of Pseudomonas aeruginosa: Role of Outer Membrane Protein OprF. PLoS ONE 7:e46857

Abstract

The fucose binding lectin LecB affects biofilm formation and is involved in pathogenicity of Pseudomonas aeruginosa. LecB resides in the outer membrane and can be released specifically by treatment of an outer membrane fraction with fucose suggesting that it binds to specific ligands. Here, we report that LecB binds to the outer membrane protein OprF. In an OprF-deficient P. aeruginosa mutant, LecB is no longer detectable in the membrane but instead in the culture supernatant indicating a specific interaction between LecB and OprF.

Links

PubMed PMC3466170 Online version:10.1371/journal.pone.0046857

Keywords


Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status


See also

References

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