PMID:22629280

Citation	Funck, D, Clauß, K, Frommer, WB and Hellmann, HA (2012) The Arabidopsis CstF64-Like RSR1/ESP1 Protein Participates in Glucose Signaling and Flowering Time Control. Front Plant Sci 3:80
Abstract	Mechanisms for sensing and regulating metabolic processes at the cellular level are critical for the general physiology and development of living organisms. In higher plants, sugar signaling is crucial for adequate regulation of carbon and energy metabolism and affects virtually every aspect of development. Although many genes are regulated by sugar levels, little is known on how sugar levels are measured by plants. Several components of the sugar signaling network have been unraveled and demonstrated to have extensive overlap with hormone signaling networks. Here we describe the reduced sugar response1-1 (rsr1-1) mutant as a new early flowering mutant that displays decreased sensitivity to abscisic acid. Both hexokinase1 (HXK1)-dependent and glucose phosphorylation-independent signaling is reduced in rsr1-1. Map-based identification of the affected locus demonstrated that rsr1-1 carries a premature stop codon in the gene for a CstF64-like putative RNA processing factor, ESP1, which is involved in mRNA 3'-end formation. The identification of RSR1/ESP1 as a nuclear protein with a potential threonine phosphorylation site may explain the impact of protein phosphorylation cascades on sugar-dependent signal transduction. Additionally, RSR1/ESP1 may be a crucial factor in linking sugar signaling to the control of flowering time.
Links	PubMed PMC3355569 Online version:10.3389/fpls.2012.00080
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Annotations

Gene product	Qualifier	GO Term	Evidence Code	with/from	Aspect	Extension	Notes	Status
ARATH:Q8VYM7		GO:2000280: regulation of root development	ECO:0000315:		P		Figure 2 shows rsr1 mutants have longer roots with morphology different from their parental type.	complete CACAO 5370
ARATH:Q8VYM7		GO:0009749: response to glucose stimulus	ECO:0000315:		P		Figure 3 shows rsr1 mutants are insensitive to glucose.	complete CACAO 5366
ARATH:Q8VYM7	involved_in	GO:0009749: response to glucose	ECO:0000315: mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete

References

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