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PMID:21959018
| Citation |
Pérez, PD, Weiss, JT and Hagen, SJ (2011) Noise and crosstalk in two quorum-sensing inputs of Vibrio fischeri. BMC Syst Biol 5:153 |
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| Abstract |
One of the puzzles in bacterial quorum sensing is understanding how an organism integrates the information gained from multiple input signals. The marine bacterium Vibrio fischeri regulates its bioluminescence through a quorum sensing mechanism that receives input from three pheromone signals, including two acyl homoserine lactone (HSL) signals. While the role of the 3-oxo-C6 homoserine lactone (3OC6HSL) signal in activating the lux genes has been extensively studied and modeled, the role of the C8 homoserine lactone (C8HSL) is less obvious, as it can either activate luminescence or block its activation. It remains unclear how crosstalk between C8HSL and 3OC6HSL affects the information that the bacterium obtains through quorum sensing. |
| Links |
PubMed PMC3224347 Online version:10.1186/1752-0509-5-153 |
| Keywords |
Aliivibrio fischeri/genetics; Aliivibrio fischeri/physiology; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Bacterial Proteins/physiology; Luminescent Measurements; Microfluidics/methods; Models, Biological; Quorum Sensing; Systems Biology |
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