PMID:21835909

Citation	Erickson, JR, Patel, R, Ferguson, A, Bossuyt, J and Bers, DM (2011) Fluorescence resonance energy transfer-based sensor Camui provides new insight into mechanisms of calcium/calmodulin-dependent protein kinase II activation in intact cardiomyocytes. Circ. Res. 109:729-38
Abstract	Calcium/calmodulin-dependent protein kinase II (CaMKII) is a key mediator of intracellular signaling in the heart. However, the tools currently available for assessing dynamic changes in CaMKII localization and activation in living myocytes are limited.
Links	PubMed PMC3182829 Online version:10.1161/CIRCRESAHA.111.247148
Keywords	Adenoviridae/genetics; Adrenergic alpha-Agonists/pharmacology; Adrenergic beta-Agonists/pharmacology; Angiotensin II/metabolism; Animals; Biosensing Techniques; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2/chemistry; Calcium-Calmodulin-Dependent Protein Kinase Type 2/genetics; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism; Cardiac Pacing, Artificial; Endothelin-1/metabolism; Enzyme Activation; Fluorescence Resonance Energy Transfer; Genetic Vectors; HEK293 Cells; Humans; Isoproterenol/pharmacology; Kinetics; Luminescent Proteins/genetics; Luminescent Proteins/metabolism; Microscopy, Confocal; Mutation; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/enzymology; Oxidation-Reduction; Phenylephrine/pharmacology; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Rabbits; Recombinant Fusion Proteins/metabolism; Structure-Activity Relationship; Transfection
edit table

Annotations

Gene product	Qualifier	GO Term	Evidence Code	with/from	Aspect	Extension	Notes	Status
RABIT:KCC2D		GO:0004683: calmodulin-dependent protein kinase activity	ECO:0000314:		F		Figure 6: Activation of CaMKII in rabbit cardiomyocytes using FRET	complete CACAO 8171

References

See Help:References for how to manage references in GONUTS.