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PMID:21437236
| Citation |
Damrauer, SM, Studer, P, da Silva, CG, Longo, CR, Ramsey, HE, Csizmadia, E, Shrikhande, GV, Scali, ST, Libermann, TA, Bhasin, MK and Ferran, C (2011) A20 modulates lipid metabolism and energy production to promote liver regeneration. PLoS ONE 6:e17715 |
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| Abstract |
Liver regeneration is clinically of major importance in the setting of liver injury, resection or transplantation. We have demonstrated that the NF-κB inhibitory protein A20 significantly improves recovery of liver function and mass following extended liver resection (LR) in mice. In this study, we explored the Systems Biology modulated by A20 following extended LR in mice. |
| Links |
PubMed PMC3060102 Online version:10.1371/journal.pone.0017715 |
| Keywords |
Animals; Binding Sites; Cell Proliferation; Energy Metabolism; Gene Expression Regulation; Gene Regulatory Networks; Hepatocytes/metabolism; Humans; Inflammation/metabolism; Inflammation/pathology; Intracellular Signaling Peptides and Proteins/metabolism; Lipid Metabolism; Liver/metabolism; Liver/pathology; Liver/surgery; Liver Regeneration/physiology; Mice; Nuclear Proteins/metabolism; Promoter Regions, Genetic/genetics; Reproducibility of Results; Transcription Factors/metabolism; Transcription, Genetic |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
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See also
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