GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:20152017
| Citation |
Gómez-Pastor, R, Pérez-Torrado, R, Cabiscol, E, Ros, J and Matallana, E (2010) Reduction of oxidative cellular damage by overexpression of the thioredoxin TRX2 gene improves yield and quality of wine yeast dry active biomass. Microb. Cell Fact. 9:9 |
|---|---|
| Abstract |
Wine Saccharomyces cerevisiae strains, adapted to anaerobic must fermentations, suffer oxidative stress when they are grown under aerobic conditions for biomass propagation in the industrial process of active dry yeast production. Oxidative metabolism of sugars favors high biomass yields but also causes increased oxidation damage of cell components. The overexpression of the TRX2 gene, coding for a thioredoxin, enhances oxidative stress resistance in a wine yeast strain model. The thioredoxin and also the glutathione/glutaredoxin system constitute the most important defense against oxidation. Trx2p is also involved in the regulation of Yap1p-driven transcriptional response against some reactive oxygen species. |
| Links |
PubMed PMC2835662 Online version:10.1186/1475-2859-9-9 |
| Keywords |
Biomass; Fermentation; Gene Expression; Glutathione/metabolism; Oxidative Stress; Saccharomyces cerevisiae/enzymology; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Saccharomyces cerevisiae Proteins/genetics; Saccharomyces cerevisiae Proteins/metabolism; Thioredoxins/genetics; Thioredoxins/metabolism; Wine/analysis; Wine/microbiology |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
See also
References
See Help:References for how to manage references in GONUTS.
