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PMID:18298954

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Citation

Galon, Y, Nave, R, Boyce, JM, Nachmias, D, Knight, MR and Fromm, H (2008) Calmodulin-binding transcription activator (CAMTA) 3 mediates biotic defense responses in Arabidopsis. FEBS Lett. 582:943-8

Abstract

Calmodulin-binding transcription activator (CAMTA) 3 (also called SR1) is a calmodulin-binding transcription factor in Arabidopsis. Two homozygous T-DNA insertion mutants (camta3-1, camta3-2) showed enhanced spontaneous lesions. Transcriptome analysis of both mutants revealed 6 genes with attenuated expression and 99 genes with elevated expression. Of the latter, 32 genes are related to defense against pathogens (e.g. WRKY33, PR1 and chitinase). Propagation of a virulent strain of the bacterial pathogen Pseudomonas syringae and the fungal pathogen Botrytis cinerea were attenuated in both mutants. Moreover, both mutants accumulated high levels of H2O2. We suggest that CAMTA3 regulates the expression of a set of genes involved in biotic defense responses.

Links

PubMed Online version:10.1016/j.febslet.2008.02.037

Keywords

Arabidopsis/genetics; Arabidopsis/microbiology; Arabidopsis Proteins/genetics; Arabidopsis Proteins/metabolism; Botrytis/growth & development; Calmodulin-Binding Proteins/genetics; Calmodulin-Binding Proteins/metabolism; Gene Expression Profiling; Gene Expression Regulation, Plant; Mutagenesis, Insertional; Plant Diseases/genetics; Plant Diseases/microbiology; Pseudomonas syringae/growth & development; Reactive Oxygen Species/metabolism; Transcription Factors/genetics; Transcription Factors/metabolism

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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