GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:18081726
| Citation |
Trosky, JE, Liverman, AD and Orth, K (2008) Yersinia outer proteins: Yops. Cell. Microbiol. 10:557-65 |
|---|---|
| Abstract |
The pathogenic bacteria Yersinia spp. contain a virulence plasmid that encodes a type III secretion system and effectors. During infection, four of the effectors target the actin cytoskeleton, crippling the phagocytic machinery in the infected cell. The remaining two effectors dampen the innate immune response by targeting important signalling pathways. Although the biochemical activity for each of these effectors is known, the mechanisms involved in their ordered secretion and delivery remain elusive. |
| Links |
PubMed Online version:10.1111/j.1462-5822.2007.01109.x |
| Keywords |
Bacterial Proteins/toxicity; Carrier Proteins/physiology; Phagocytosis/immunology; Plasmids; Signal Transduction/immunology; Virulence; Yersinia/immunology; Yersinia/pathogenicity |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0035335: peptidyl-tyrosine dephosphorylation |
ECO:0000315: |
P |
Figure 1: Displays the YopH removing a phosphate group from protein X. |
complete | ||||
| GO:0004725: protein tyrosine phosphatase activity |
ECO:0000315: |
F |
Section 4 |
complete | ||||
See also
References
See Help:References for how to manage references in GONUTS.
