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PMID:18025791

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Citation

Trzpis, M, Popa, ER, McLaughlin, PM, van Goor, H, Timmer, A, Bosman, GW, de Leij, LM and Harmsen, MC (2007) Spatial and temporal expression patterns of the epithelial cell adhesion molecule (EpCAM/EGP-2) in developing and adult kidneys. Nephron Exp. Nephrol. 107:e119-31

Abstract

The epithelial cell adhesion molecule (EpCAM) is expressed by most epithelia and is involved in processes fundamental for morphogenesis, including cell-cell adhesion, proliferation, differentiation, and migration. Previously, a role for EpCAM in pancreatic morphogenesis was confirmed in vitro. Furthermore, changes in the EpCAM expression pattern were found in developing lung and thymus and in the regenerating liver. Therefore, EpCAM was proposed to be a morphoregulatory molecule.

Links

PubMed Online version:10.1159/111039

Keywords

Adult; Age Factors; Animals; Animals, Newborn; Antibodies, Monoclonal; Antigens, Neoplasm/immunology; Antigens, Neoplasm/metabolism; CHO Cells; Cell Adhesion Molecules/immunology; Cell Adhesion Molecules/metabolism; Cell Polarity; Cricetinae; Cricetulus; Epithelial Cells/cytology; Epithelial Cells/metabolism; Female; Humans; Immunohistochemistry; Kidney/embryology; Kidney/growth & development; Kidney/physiology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Staining and Labeling

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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