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PMID:18025791
Citation |
Trzpis, M, Popa, ER, McLaughlin, PM, van Goor, H, Timmer, A, Bosman, GW, de Leij, LM and Harmsen, MC (2007) Spatial and temporal expression patterns of the epithelial cell adhesion molecule (EpCAM/EGP-2) in developing and adult kidneys. Nephron Exp. Nephrol. 107:e119-31 |
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Abstract |
The epithelial cell adhesion molecule (EpCAM) is expressed by most epithelia and is involved in processes fundamental for morphogenesis, including cell-cell adhesion, proliferation, differentiation, and migration. Previously, a role for EpCAM in pancreatic morphogenesis was confirmed in vitro. Furthermore, changes in the EpCAM expression pattern were found in developing lung and thymus and in the regenerating liver. Therefore, EpCAM was proposed to be a morphoregulatory molecule. |
Links |
PubMed Online version:10.1159/111039 |
Keywords |
Adult; Age Factors; Animals; Animals, Newborn; Antibodies, Monoclonal; Antigens, Neoplasm/immunology; Antigens, Neoplasm/metabolism; CHO Cells; Cell Adhesion Molecules/immunology; Cell Adhesion Molecules/metabolism; Cell Polarity; Cricetinae; Cricetulus; Epithelial Cells/cytology; Epithelial Cells/metabolism; Female; Humans; Immunohistochemistry; Kidney/embryology; Kidney/growth & development; Kidney/physiology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Staining and Labeling |
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Significance
Annotations
Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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