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PMID:17897480
Citation |
Byrne, AB, Weirauch, MT, Wong, V, Koeva, M, Dixon, SJ, Stuart, JM and Roy, PJ (2007) A global analysis of genetic interactions in Caenorhabditis elegans. J. Biol. 6:8 |
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Abstract |
Understanding gene function and genetic relationships is fundamental to our efforts to better understand biological systems. Previous studies systematically describing genetic interactions on a global scale have either focused on core biological processes in protozoans or surveyed catastrophic interactions in metazoans. Here, we describe a reliable high-throughput approach capable of revealing both weak and strong genetic interactions in the nematode Caenorhabditis elegans. |
Links |
PubMed PMC2373897 Online version:10.1186/jbiol58 |
Keywords |
Animals; Caenorhabditis elegans/genetics; Caenorhabditis elegans Proteins/genetics; Caenorhabditis elegans Proteins/metabolism; Models, Genetic; RNA Interference |
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Significance
Annotations
Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
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See also
References
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