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PMID:17897480

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Citation

Byrne, AB, Weirauch, MT, Wong, V, Koeva, M, Dixon, SJ, Stuart, JM and Roy, PJ (2007) A global analysis of genetic interactions in Caenorhabditis elegans. J. Biol. 6:8

Abstract

Understanding gene function and genetic relationships is fundamental to our efforts to better understand biological systems. Previous studies systematically describing genetic interactions on a global scale have either focused on core biological processes in protozoans or surveyed catastrophic interactions in metazoans. Here, we describe a reliable high-throughput approach capable of revealing both weak and strong genetic interactions in the nematode Caenorhabditis elegans.

Links

PubMed PMC2373897 Online version:10.1186/jbiol58

Keywords

Animals; Caenorhabditis elegans/genetics; Caenorhabditis elegans Proteins/genetics; Caenorhabditis elegans Proteins/metabolism; Models, Genetic; RNA Interference

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

See also

References

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