GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:17872410
Citation |
Sawa, M, Nusinow, DA, Kay, SA and Imaizumi, T (2007) FKF1 and GIGANTEA complex formation is required for day-length measurement in Arabidopsis. Science 318:261-5 |
---|---|
Abstract |
Precise timing of CONSTANS (CO) gene expression is necessary for day-length discrimination for photoperiodic flowering. The FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1), and GIGANTEA (GI) proteins regulate CO transcription in Arabidopsis. We demonstrate that FKF1 and GI proteins form a complex in a blue-light-dependent manner. The timing of this interaction regulates the timing of daytime CO expression. FKF1 function is dependent on GI, which interacts with a CO repressor, CYCLING DOF FACTOR 1 (CDF1), and controls CDF1 stability. GI, FKF1, and CDF1 proteins associate with CO chromatin. Thus, the FKF1-GI complex forms on the CO promoter in late afternoon to regulate CO expression, providing a mechanistic view of how the coincidence of light with circadian timing regulates photoperiodic flowering. |
Links |
PubMed Online version:10.1126/science.1146994 |
Keywords |
Arabidopsis/genetics; Arabidopsis/physiology; Arabidopsis Proteins/chemistry; Arabidopsis Proteins/genetics; Arabidopsis Proteins/metabolism; Chromatin/metabolism; Chromatin Immunoprecipitation; Circadian Rhythm; DNA-Binding Proteins/genetics; Flowers/genetics; Flowers/growth & development; Gene Expression Regulation, Plant; Light; Mutation; Photoperiod; Plants, Genetically Modified; Promoter Regions, Genetic; Protein Structure, Tertiary; Recombinant Fusion Proteins/metabolism; Repressor Proteins/metabolism; Transcription Factors/genetics |
edit table |
Significance
Annotations
Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
---|---|---|---|---|---|---|---|---|
edit table |
See also
References
See Help:References for how to manage references in GONUTS.