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PMID:17827287
| Citation |
Antunes, LC, Schaefer, AL, Ferreira, RB, Qin, N, Stevens, AM, Ruby, EG and Greenberg, EP (2007) Transcriptome analysis of the Vibrio fischeri LuxR-LuxI regulon. J. Bacteriol. 189:8387-91 |
|---|---|
| Abstract |
The Vibrio fischeri quorum-sensing signal N-3-oxohexanoyl-l-homoserine lactone (3OC6-HSL) activates expression of the seven-gene luminescence operon. We used microarrays to unveil 18 additional 3OC6-HSL-controlled genes, 3 of which had been identified by other means previously. We show most of these genes are regulated by the 3OC6-HSL-responsive transcriptional regulator LuxR directly. This demonstrates that V. fischeri quorum sensing regulates a substantial number of genes other than those involved in light production. |
| Links |
PubMed PMC2168698 Online version:10.1128/JB.00736-07 |
| Keywords |
4-Butyrolactone/analogs & derivatives; 4-Butyrolactone/metabolism; Aliivibrio fischeri/genetics; Bacterial Proteins/genetics; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Luminescence; Oligonucleotide Array Sequence Analysis; Operon; Promoter Regions, Genetic; Protein Binding; Quorum Sensing; Regulon/genetics; Repressor Proteins/genetics; Trans-Activators/genetics; Transcription Factors/genetics |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0061579: N-acyl homoserine lactone synthase activity |
ECO:0000317: |
UniProtKB:P12747
|
F |
complete | ||||
Notes
See also
References
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