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PMID:17634100

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Citation

French, CR, Erickson, T, Callander, D, Berry, KM, Koss, R, Hagey, DW, Stout, J, Wuennenberg-Stapleton, K, Ngai, J, Moens, CB and Waskiewicz, AJ (2007) Pbx homeodomain proteins pattern both the zebrafish retina and tectum. BMC Dev. Biol. 7:85

Abstract

Pbx genes encode TALE class homeodomain transcription factors that pattern the developing neural tube, pancreas, and blood. Within the hindbrain, Pbx cooperates with Hox proteins to regulate rhombomere segment identity. Pbx cooperates with Eng to regulate midbrain-hindbrain boundary maintenance, and with MyoD to control fast muscle cell differentiation. Although previous results have demonstrated that Pbx is required for proper eye size, functions in regulating retinal cell identity and patterning have not yet been examined.

Links

PubMed PMC1934912 Online version:10.1186/1471-213X-7-85

Keywords

Animals; Body Patterning/genetics; DNA-Binding Proteins/genetics; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Homeodomain Proteins/genetics; In Situ Hybridization; Molecular Probes; Oligonucleotide Array Sequence Analysis; Retina/embryology; Retinal Ganglion Cells/physiology; Superior Colliculi/embryology; Zebrafish/embryology; Zebrafish/genetics; Zebrafish Proteins/genetics

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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