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PMID:17460765
| Citation |
Ribeiro, I, Kawakami, Y, Büscher, D, Raya, A, Rodríguez-León, J, Morita, M, Rodríguez Esteban, C and Izpisúa Belmonte, JC (2007) Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling. PLoS ONE 2:e398 |
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| Abstract |
The heart forms from a linear tube that is subject to complex remodeling during embryonic development. Hallmarks of this remodeling are the looping of the heart tube and the regionalization into chamber and non-chamber myocardium. Cardiomyocytes in the future chamber myocardium acquire different cellular and physiological characteristics through activation of a chamber-specific genetic program, which is in part mediated by T-box genes. |
| Links |
PubMed PMC1851989 Online version:10.1371/journal.pone.0000398 |
| Keywords |
Animals; Cell Proliferation; Gene Expression Regulation, Developmental; Heart/physiology; Transcription Factors/genetics; Transcription Factors/physiology; Zebrafish |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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