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PMID:17382917
| Citation |
Hou, Y, Okamoto, C, Okada, K, Kawao, N, Kawata, S, Ueshima, S and Matsuo, O (2007) c-Myc is essential for urokinase plasminogen activator expression on hypoxia-induced vascular smooth muscle cells. Cardiovasc. Res. 75:186-94 |
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| Abstract |
The purpose of this study was to investigate whether c-Myc regulates expression of urokinase plasminogen activator (uPA) on hypoxia-induced vascular smooth muscle cells (VSMCs). |
| Links |
PubMed Online version:10.1016/j.cardiores.2007.02.033 |
| Keywords |
Animals; Anoxia/metabolism; Blood Vessels; Blotting, Western/methods; Cell Movement; Cell Proliferation; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Gene Expression; Genes, bcl-2; Genes, myc; Luciferases/genetics; Matrix Metalloproteinases/genetics; Matrix Metalloproteinases/metabolism; Mice; Mice, Knockout; Myocytes, Smooth Muscle/metabolism; Proto-Oncogene Proteins c-myc/metabolism; RNA Interference; RNA, Small Interfering/pharmacology; Reverse Transcriptase Polymerase Chain Reaction; Tissue Plasminogen Activator/genetics; Tissue Plasminogen Activator/metabolism; Urokinase-Type Plasminogen Activator/genetics; Urokinase-Type Plasminogen Activator/metabolism |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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