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PMID:17233889
| Citation |
de Bruin, OM, Ludu, JS and Nano, FE (2007) The Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growth. BMC Microbiol. 7:1 |
|---|---|
| Abstract |
Francisella tularensis is a gram negative, facultative intracellular bacterium that is the etiological agent of tularemia. F. novicida is closely related to F. tularensis but has low virulence for humans while being highly virulent in mice. IglA is a 21 kDa protein encoded by a gene that is part of an iglABCD operon located on the Francisella pathogenicity island (FPI). |
| Links |
PubMed PMC1794414 Online version:10.1186/1471-2180-7-1 |
| Keywords |
Animals; Bacterial Proteins/biosynthesis; Bacterial Proteins/genetics; Bacterial Proteins/physiology; Cell Fractionation; Computational Biology; Cytoplasm/chemistry; Francisella tularensis/chemistry; Francisella tularensis/genetics; Francisella tularensis/growth & development; Francisella tularensis/pathogenicity; Gene Deletion; Gene Expression Regulation, Bacterial/physiology; Genetic Complementation Test; Genomic Islands/genetics; Immunoprecipitation; Macrophages/microbiology; Mice; Mutagenesis, Insertional; Protein Binding; Protein Transport/genetics |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737: cytoplasm |
IDA: Inferred from Direct Assay: |
C |
Figure 4 |
complete |
| |||
| GO:0005625: soluble fraction |
ECO:0000314: |
C |
Figure 4 |
complete | ||||
See also
References
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