GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:16723478
Citation |
Gosbell, AD, Stefanovic, N, Scurr, LL, Pete, J, Kola, I, Favilla, I and de Haan, JB (2006) Retinal light damage: structural and functional effects of the antioxidant glutathione peroxidase-1. Invest. Ophthalmol. Vis. Sci. 47:2613-22 |
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Abstract |
The role of the antioxidant enzyme glutathione peroxidase-1 (GPx1) in protecting the retina against photo-oxidative damage was investigated in GPx1-deficient and wild-type mice. |
Links |
PubMed Online version:10.1167/iovs.05-0962 |
Keywords |
Animals; Antioxidants/physiology; Catalase/metabolism; Electroretinography/radiation effects; Gene Expression Regulation; Glutaredoxins; Glutathione Peroxidase/deficiency; Glutathione Peroxidase/physiology; Light; Lipid Peroxidation; Male; Membrane Proteins/genetics; Membrane Proteins/metabolism; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidative Stress; Oxidoreductases/genetics; Oxidoreductases/metabolism; Peroxidases/genetics; Peroxidases/metabolism; Peroxiredoxin VI; Peroxiredoxins; RNA, Messenger/metabolism; Radiation Injuries, Experimental/enzymology; Radiation Injuries, Experimental/physiopathology; Retina/physiopathology; Retina/radiation effects; Retinal Diseases/enzymology; Retinal Diseases/physiopathology; Reverse Transcriptase Polymerase Chain Reaction; Thiobarbituric Acid Reactive Substances; Thioredoxins/genetics; Thioredoxins/metabolism; Up-Regulation |
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Significance
Annotations
Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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