PMID:16679419

Citation	Morris, ER, Chevalier, D and Walker, JC (2006) DAWDLE, a forkhead-associated domain gene, regulates multiple aspects of plant development. Plant Physiol. 141:932-41
Abstract	Phosphoprotein-binding domains are found in many different proteins and specify protein-protein interactions critical for signal transduction pathways. Forkhead-associated (FHA) domains bind phosphothreonine and control many aspects of cell proliferation in yeast (Saccharomyces cerevisiae) and animal cells. The Arabidopsis (Arabidopsis thaliana) protein kinase-associated protein phosphatase includes a FHA domain that mediates interactions with receptor-like kinases, which in turn regulate a variety of signaling pathways involved in plant growth and pathogen responses. Screens for insertional mutations in other Arabidopsis FHA domain-containing genes identified a mutant with pleiotropic defects. dawdle (ddl) plants are developmentally delayed, produce defective roots, shoots, and flowers, and have reduced seed set. DDL is expressed in the root and shoot meristems and the reduced size of the root apical meristem in ddl plants suggests a role early in organ development.
Links	PubMed PMC1489914 Online version:10.1104/pp.106.076893
Keywords	Alleles; Arabidopsis/anatomy & histology; Arabidopsis/genetics; Arabidopsis/growth & development; Arabidopsis Proteins/metabolism; Arabidopsis Proteins/physiology; Carrier Proteins/metabolism; Carrier Proteins/physiology; Fertility/genetics; Flowers/anatomy & histology; Gene Expression; Genes, Plant; Meristem/physiology; Molecular Sequence Data; Mutation; Protein Structure, Tertiary
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Gene product	Qualifier	GO ID	GO term name	Evidence Code	with/from	Aspect	Notes	Status
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