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PMID:16492771
| Citation |
Lorch, Y, Maier-Davis, B and Kornberg, RD (2006) Chromatin remodeling by nucleosome disassembly in vitro. Proc. Natl. Acad. Sci. U.S.A. 103:3090-3 |
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| Abstract |
The RSC chromatin-remodeling complex completely disassembles a nucleosome in the presence of the histone chaperone Nap1 and ATP. Disassembly occurs in a stepwise manner, with the removal of H2A/H2B dimers, followed by the rest of the histones and the release of naked DNA. RSC and related chromatin-remodeling complexes may be responsible for the removal of promoter nucleosomes during transcriptional activation in vivo. |
| Links |
PubMed PMC1413907 Online version:10.1073/pnas.0511050103 |
| Keywords |
Animals; Chromatin Assembly and Disassembly/genetics; Histones/metabolism; Nucleosomes/chemistry; Nucleosomes/genetics; Nucleosomes/metabolism; Promoter Regions, Genetic/genetics; Protein Binding; Rats; Transcriptional Activation |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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