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PMID:1641037
| Citation |
Hill, RJ and Sternberg, PW (1992) The gene lin-3 encodes an inductive signal for vulval development in C. elegans. Nature 358:470-6 |
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| Abstract |
The lin-3 gene is necessary for induction of the Caenorhabditis elegans vulva by the anchor cell. It encodes a molecule similar to epidermal growth factor and to transforming growth factor-alpha and acts through the epidermal growth factor receptor homologue let-23. Expression of lin-3 in the anchor cell stimulates vulval induction; lin-3 may encode the vulval inducing signal. |
| Links |
PubMed Online version:10.1038/358470a0 |
| Keywords |
Amino Acid Sequence; Animals; Animals, Genetically Modified; Base Sequence; Caenorhabditis/embryology; Caenorhabditis/genetics; Caenorhabditis elegans Proteins; Cloning, Molecular; Disorders of Sex Development; Embryonic Induction/genetics; Epidermal Growth Factor/genetics; Female; Helminth Proteins/genetics; Molecular Sequence Data; Recombinant Fusion Proteins; Stem Cells/physiology; Vulva/embryology |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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