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PMID:15840165
| Citation |
Maduzia, LL, Roberts, AF, Wang, H, Lin, X, Chin, LJ, Zimmerman, CM, Cohen, S, Feng, XH and Padgett, RW (2005) C. elegans serine-threonine kinase KIN-29 modulates TGFbeta signaling and regulates body size formation. BMC Dev. Biol. 5:8 |
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| Abstract |
In C. elegans there are two well-defined TGFbeta-like signaling pathways. The Sma/Mab pathway affects body size morphogenesis, male tail development and spicule formation while the Daf pathway regulates entry into and exit out of the dauer state. To identify additional factors that modulate TGFbeta signaling in the Sma/Mab pathway, we have undertaken a genetic screen for small animals and have identified kin-29. |
| Links |
PubMed PMC1112587 Online version:10.1186/1471-213X-5-8 |
| Keywords |
Amino Acid Sequence; Animals; Caenorhabditis elegans/anatomy & histology; Caenorhabditis elegans/enzymology; Caenorhabditis elegans/genetics; Caenorhabditis elegans/growth & development; Caenorhabditis elegans Proteins/chemistry; Caenorhabditis elegans Proteins/genetics; Caenorhabditis elegans Proteins/physiology; Epistasis, Genetic; Gene Expression Regulation, Developmental; Genes, Helminth; Male; Molecular Sequence Data; Morphogenesis/genetics; Mutation; Neurons/enzymology; Neuropeptides/genetics; Neuropeptides/physiology; Protein-Serine-Threonine Kinases/chemistry; Protein-Serine-Threonine Kinases/genetics; Protein-Serine-Threonine Kinases/physiology; RNA/genetics; Signal Transduction/genetics; Subcutaneous Tissue/enzymology; Transforming Growth Factor beta/genetics; Transforming Growth Factor beta/physiology |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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