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PMID:15749075
| Citation |
Murphy, K, Carvajal, L, Medico, L and Pepling, M (2005) Expression of Stat3 in germ cells of developing and adult mouse ovaries and testes. Gene Expr. Patterns 5:475-82 |
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| Abstract |
The Signal transducers and activators of transcription (Stat) family of proteins plays diverse roles during differentiation in many tissues. Stat3 is an essential mammalian gene, critical during embryonic development. In mammals, Stat3 is differentially distributed in the cytoplasm of mature oocytes and in preimplantation embryos suggesting that Stat3 may be involved in determination of polarity. Here, we report that Stat3 protein is expressed in the cytoplasm of oocytes from primordial, primary and secondary follicles in the adult ovary and in developing acrosomes of round spermatids in the adult testis. Stat3 is also expressed in gonocytes, prospermatogonia, oogonia and oocytes of embryonic and neonatal gonads. |
| Links |
PubMed Online version:10.1016/j.modgep.2004.12.007 |
| Keywords |
Animals; Blastula/physiology; DNA Primers; DNA-Binding Proteins/genetics; Embryo Implantation; Embryonic Development; Female; Gene Expression Regulation, Developmental; Immunohistochemistry; Male; Mammals; Mice; Oocytes; Ovary/embryology; Ovary/physiology; Ovum/physiology; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; Spermatids/physiology; Spermatozoa/physiology; Testis/embryology; Testis/physiology; Trans-Activators/genetics |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
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