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PMID:15661395

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Citation

Asari, S, Sakamoto, A, Okada, S, Ohkubo, Y, Arima, M, Hatano, M, Kuroda, Y and Tokuhisa, T (2005) Abnormal erythroid differentiation in neonatal bcl-6-deficient mice. Exp. Hematol. 33:26-34

Abstract

The bcl-6 proto-oncogene is ubiquitously expressed in various tissues. Since we found out the smaller number of TER119(+) cells in the spleen of neonatal bcl-6-deficient (bcl-6(-/-)) mice compared with that of control (bcl-6(+/+)) littermates, we studied functions of bcl-6 in differentiation of erythroid lineage cells.

Links

PubMed Online version:10.1016/j.exphem.2004.10.001

Keywords

Animals; Animals, Newborn; Antigens, CD/analysis; Antigens, Differentiation, B-Lymphocyte/analysis; Blood Group Antigens/analysis; Cell Differentiation; Cell Proliferation; DNA-Binding Proteins/deficiency; DNA-Binding Proteins/physiology; Erythroblasts/cytology; Erythrocyte Count; Erythrocytes/cytology; Erythrocytes/physiology; Erythropoiesis; Mice; Mice, Knockout; Proto-Oncogene Proteins/deficiency; Proto-Oncogene Proteins/physiology; Proto-Oncogene Proteins c-bcl-6; Receptors, Transferrin; Reticulocytes/cytology; Spleen/cytology; Transcription Factors/deficiency; Transcription Factors/physiology

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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