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PMID:15519652
| Citation |
Shiojiri, N, Takeshita, K, Yamasaki, H and Iwata, T (2004) Suppression of C/EBP alpha expression in biliary cell differentiation from hepatoblasts during mouse liver development. J. Hepatol. 41:790-8 |
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| Abstract |
Intrahepatic biliary cell differentiation takes place in periportal hepatoblasts under the influence of the subjacent mesenchyme, which leads to the suppression of mature hepatocyte marker expression. This study was undertaken to analyze C/EBP alpha and beta expression, which may govern transcription of mature hepatocyte marker genes, during mouse liver development with special attention given to biliary differentiation. |
| Links |
PubMed Online version:10.1016/j.jhep.2004.07.011 |
| Keywords |
Albumins/genetics; Animals; Antibodies; Biliary Tract/cytology; Biliary Tract/embryology; CCAAT-Enhancer-Binding Protein-alpha/genetics; CCAAT-Enhancer-Binding Protein-alpha/immunology; CCAAT-Enhancer-Binding Protein-alpha/metabolism; CCAAT-Enhancer-Binding Protein-beta/genetics; CCAAT-Enhancer-Binding Protein-beta/immunology; CCAAT-Enhancer-Binding Protein-beta/metabolism; Carbamoyl-Phosphate Synthase (Ammonia)/genetics; Cell Differentiation/physiology; Epithelial Cells/cytology; Female; Gene Expression Regulation, Developmental; Hepatocytes/cytology; Liver/cytology; Liver/embryology; Mice; Mice, Inbred C3H; Ornithine Carbamoyltransferase/genetics; Pregnancy; RNA, Messenger/analysis; alpha-Fetoproteins/genetics |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
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