GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:1501243
| Citation |
Hernández-Sotomayor, SM and Carpenter, G (1992) Epidermal growth factor receptor: elements of intracellular communication. J. Membr. Biol. 128:81-9 |
|---|---|
| Abstract |
While EGF has an important function in cell growth regulation, the molecular mechanisms by which intracellular signal connect the EGF: receptor complex on the plasma membrane with the initiation of DNA synthesis and mitogenesis is not well understood. The discovery that rasGAP, PI-3 kinase and PLC-gamma 1 are substrates for the EGF receptor tyrosine kinase has provided a beginning in understanding the biochemistry underlying growth factor receptor transduction. |
| Links | |
| Keywords |
Phosphorylation; Receptor, Epidermal Growth Factor/metabolism; Signal Transduction; Tyrosine/metabolism |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0007165: signal transduction |
EXP: Inferred from Experiment: : |
P |
| |||||
See also
References
See Help:References for how to manage references in GONUTS.
