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PMID:12185400
| Citation |
Chausmer, AL, Elmer, GI, Rubinstein, M, Low, MJ, Grandy, DK and Katz, JL (2002) Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice. Psychopharmacology (Berl.) 163:54-61 |
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| Abstract |
Dopamine (DA) D2-like antagonists block several effects of cocaine, including its locomotor stimulant and interoceptive discriminative-stimulus effects. Because these compounds generally lack selectivity among the D2-like DA receptors, the specific roles of the subtypes remain unclear. |
| Links |
PubMed Online version:10.1007/s00213-002-1142-y |
| Keywords |
Animals; Cocaine/pharmacology; Discrimination (Psychology)/drug effects; Dopamine Antagonists/pharmacology; Dopamine Uptake Inhibitors/pharmacology; Dose-Response Relationship, Drug; Female; Genotype; Male; Mice; Mice, Knockout; Motor Activity/drug effects; Raclopride/pharmacology; Receptors, Dopamine D2/deficiency; Receptors, Dopamine D2/genetics |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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