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Brady, JP, Garland, DL, Green, DE, Tamm, ER, Giblin, FJ and Wawrousek, EF (2001) AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach. Invest. Ophthalmol. Vis. Sci. 42:2924-34
To study the role of alphaB-crystallin (alphaB) in the developing lens and its importance in lens structure and function.
Aging/pathology; Animals; Bacterial Proteins; Blotting, Northern; Blotting, Southern; Crystallins/physiology; Electrophoresis, Gel, Two-Dimensional; Gene Deletion; Heat-Shock Proteins/physiology; Kyphosis/diagnosis; Kyphosis/etiology; Kyphosis/metabolism; Lens, Crystalline/growth & development; Lens, Crystalline/metabolism; Mice; Mice, Knockout; Molecular Chaperones/metabolism; Muscle, Skeletal/metabolism; Muscle, Skeletal/pathology; Muscular Dystrophies/etiology; Muscular Dystrophies/metabolism; Muscular Dystrophies/pathology; Oxidative Stress; RNA, Messenger/metabolism
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