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PMID:11514528
| Citation |
Hullo, MF, Moszer, I, Danchin, A and Martin-Verstraete, I (2001) CotA of Bacillus subtilis is a copper-dependent laccase. J. Bacteriol. 183:5426-30 |
|---|---|
| Abstract |
The spore coat protein CotA of Bacillus subtilis displays similarities with multicopper oxidases, including manganese oxidases and laccases. B. subtilis is able to oxidize manganese, but neither CotA nor other sporulation proteins are involved. We demonstrate that CotA is a laccase. Syringaldazine, a specific substrate of laccases, reacted with wild-type spores but not with DeltacotA spores. CotA may participate in the biosynthesis of the brown spore pigment, which appears to be a melanin-like product and to protect against UV light. |
| Links | |
| Keywords |
Bacillus subtilis/enzymology; Bacillus subtilis/radiation effects; Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Binding Sites; Copper/metabolism; Culture Media; Laccase; Manganese/metabolism; Melanins/metabolism; Oxidoreductases/chemistry; Oxidoreductases/genetics; Oxidoreductases/metabolism; Pigments, Biological/metabolism; Spores, Bacterial/metabolism; Ultraviolet Rays |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0052716: hydroquinone:oxygen oxidoreductase activity |
ECO:0000315: mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
See also
References
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