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PMID:11384650

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Citation

Hefler, LA and Gregg, AR (2001) Influence of the angiotensinogen gene on the ovulatory capacity of mice. Fertil. Steril. 75:1206-11

Abstract

The tissue-bound ovarian renin-angiotensin system (OVRAS) is critically involved in ovulation in humans and rodents. Mice with disruption and overexpression of the angiotensinogen gene (Agt) have been previously generated. We investigated the influence of varying Agt gene expression on the ovulatory capacity and early embryonic development in mice.

Links

PubMed

Keywords

Angiotensinogen/genetics; Animals; Cells, Cultured; Embryo, Mammalian/physiology; Embryonic and Fetal Development; Estradiol/blood; Female; Gene Dosage; Mice; Mice, Mutant Strains; Ovary/cytology; Ovulation/genetics; Superovulation; Zygote/physiology

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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