GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:11290328
| Citation |
Jones, LJ, Carballido-López, R and Errington, J (2001) Control of cell shape in bacteria: helical, actin-like filaments in Bacillus subtilis. Cell 104:913-22 |
|---|---|
| Abstract |
In the absence of an overt cytoskeleton, the external cell wall of bacteria has traditionally been assumed to be the primary determinant of cell shape. In the Gram-positive bacterium Bacillus subtilis, two related genes, mreB and mbl, were shown to be required for different aspects of cell morphogenesis. Subcellular localization of the MreB and Mbl proteins revealed that each forms a distinct kind of filamentous helical structure lying close to the cell surface. The distribution of the proteins in different species of bacteria, and the similarity of their sequence to eukaryotic actins, suggest that the MreB-like proteins have a cytoskeletal, actin-like role in bacterial cell morphogenesis. |
| Links | |
| Keywords |
Actins/chemistry; Actins/genetics; Actins/metabolism; Amino Acid Sequence; Animals; Bacillus subtilis/cytology; Bacillus subtilis/genetics; Bacillus subtilis/growth & development; Bacteria/genetics; Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Cytoskeletal Proteins; Escherichia coli Proteins; Genes, Bacterial; Humans; Molecular Sequence Data; Morphogenesis; Sequence Alignment; Sequence Homology, Amino Acid |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005856: cytoskeleton |
ECO:0000314: |
C |
Figure 2. Subcellular Localization of MreB Protein in B. subtilis |
complete | ||||
| GO:0000902: cell morphogenesis |
ECO:0000315: |
P |
Figure 1. Contrasting Effects of Mutations in the mreB and mbl Genes on Cell Shape, as Determined by Phase Contrast Microscopy |
complete | ||||
| GO:0000902: cell morphogenesis |
ECO:0000315: |
P |
Figure 1. Contrasting Effects of Mutations in the mreB and mbl Genes on Cell Shape, as Determined by Phase Contrast Microscopy |
complete | ||||
| GO:0005856: cytoskeleton |
ECO:0000314: |
C |
Figure 3. Subcellular Localization of Mbl |
complete | ||||
See also
References
See Help:References for how to manage references in GONUTS.
