GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:11172592
| Citation |
Bernard-Gallon, DJ, De Latour, MP, Sylvain, V, Vissac, C, Aunoble, B, Chassagne, J and Bignon, YJ (2001) Brca1 and Brca2 protein expression patterns in different tissues of murine origin. Int. J. Oncol. 18:271-80 |
|---|---|
| Abstract |
We have analyzed by immunohistochemistry Brca1 and Brca2 protein expression in mouse during embryonic development, in adult tissues, and during postnatal mammary gland development. Our observations confirm previous localization of Brca1 and Brca2 mRNA on frozen sections by in situ hybridization, and demonstrate that Brca1 and Brca2 proteins are expressed in rapidly proliferating cell types undergoing differentiation. These results imply that Brca1 and Brca2 proteins are involved in the process of proliferation and differentiation in multiple tissues, notably in the mammary gland during pregnancy and lactation. |
| Links | |
| Keywords |
Animals; BRCA1 Protein/metabolism; BRCA2 Protein; Brain/embryology; Brain/metabolism; Embryonic and Fetal Development/physiology; Female; Immunohistochemistry; Mammary Glands, Animal/growth & development; Mammary Glands, Animal/metabolism; Mice; Mice, Inbred C57BL; Neoplasm Proteins/metabolism; Pregnancy; Transcription Factors/metabolism |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| edit table |
See also
References
See Help:References for how to manage references in GONUTS.
