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PMID:11172440
| Citation |
Kim, PC, Mo, R and Hui Cc, C (2001) Murine models of VACTERL syndrome: Role of sonic hedgehog signaling pathway. J. Pediatr. Surg. 36:381-4 |
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| Abstract |
VACTERL syndrome is a common surgical condition affecting the development of many midaxial organs. The etiology, embryology, and pathogenesis of the VACTERL syndrome are not known. The authors report here new mouse models of VACTERL syndrome involving the Sonic hedgehog (Shh) signaling pathway. |
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| Keywords |
Abnormalities, Multiple/metabolism; Animals; Disease Models, Animal; Esophagus/abnormalities; Heart Defects, Congenital; Kidney/abnormalities; Limb Deformities, Congenital; Membrane Proteins/metabolism; Mice; Mice, Mutant Strains; Receptors, Cell Surface; Spine/abnormalities; Syndrome; Trachea/abnormalities |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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