PMID:11108847

Citation	Magyar, Z, Atanassova, A, De Veylder, L, Rombauts, S and Inzé, D (2000) Characterization of two distinct DP-related genes from Arabidopsis thaliana. FEBS Lett. 486:79-87
Abstract	E2F/DP complexes play a pivotal role in the regulation of the G1/S transition in animals. Recently, plant E2F homologs have been cloned, but DP-related sequences have not been identified so far. Here we report that Arabidopsis thaliana contains at least two different DP-related genes, AtDPa and AtDPb. They exhibit an overall domain organization similar to that of their animal counterparts, although phylogenetic analysis demonstrated that they form a separate subgroup. AtDPs efficiently heterodimerize in vitro with the Arabidopsis E2F-related proteins, AtE2Fa and AtE2Fb through their dimerization domains. AtDPa and AtE2Fa are predominantly produced in actively dividing cells with highest transcript levels in early S phase cells.
Links	PubMed
Keywords	Amino Acid Sequence; Animals; Arabidopsis/genetics; Binding Sites; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; DNA-Binding Proteins; Dimerization; E2F Transcription Factors; Gene Expression Regulation, Plant; Genes, Plant/genetics; Humans; Molecular Sequence Data; Mutation/genetics; Organ Specificity; Phylogeny; Plant Proteins/chemistry; Plant Proteins/genetics; Plant Proteins/metabolism; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Plant/genetics; RNA, Plant/metabolism; Retinoblastoma-Binding Protein 1; Sequence Alignment; Transcription Factor DP1; Transcription Factors/chemistry; Transcription Factors/genetics; Transcription Factors/metabolism; Two-Hybrid System Techniques
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