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PMID:10847687
| Citation |
Nelson, DC, Lasswell, J, Rogg, LE, Cohen, MA and Bartel, B (2000) FKF1, a clock-controlled gene that regulates the transition to flowering in Arabidopsis. Cell 101:331-40 |
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| Abstract |
Plant reproduction requires precise control of flowering in response to environmental cues. We isolated a late-flowering Arabidopsis mutant, fkf1, that is rescued by vemalization or gibberellin treatment. We positionally cloned FKF1, which encodes a novel protein with a PAS domain similar to the flavin-binding region of certain photoreceptors, an F box characteristic of proteins that direct ubiquitin-mediated degradation, and six kelch repeats predicted to fold into a beta propeller. FKF1 mRNA levels oscillate with a circadian rhythm, and deletion of FKF1 alters the waveform of rhythmic expression of two clock-controlled genes, implicating FKF1 in modulating the Arabidopsis circadian clock. |
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| Keywords |
Amino Acid Sequence; Arabidopsis/genetics; Arabidopsis/physiology; Arabidopsis Proteins; Base Sequence; Biological Clocks/physiology; Circadian Rhythm; DNA, Plant; Genes, Plant; Hypocotyl; Light; Molecular Sequence Data; Plant Proteins/genetics; Plant Proteins/physiology; RNA, Messenger |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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