GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:10830258
| Citation |
Shan, L, He, P, Zhou, JM and Tang, X (2000) A cluster of mutations disrupt the avirulence but not the virulence function of AvrPto. Mol. Plant Microbe Interact. 13:592-8 |
|---|---|
| Abstract |
avrPto in Pseudomonas syringae pv. tomato encodes an avirulence protein that triggers race-specific resistance in tomato plants carrying Pto. The AvrPto protein is secreted from P. syringae pv. tomato to plant cells through the type III secretion pathway and activates race-specific resistance by a direct interaction with the Pto protein. Here we report that avrPto enhances the virulence of P. syringae pv. tomato in a strain-dependent manner in tomato plants lacking Pto. To determine whether the virulence function can be structurally separated from the avirulence function, we examined the virulence activity of a group of AvrPto mutants that carry single amino acid substitutions and lack the avirulence activity on tomato plants. Three mutants that were clustered in the center of AvrPto exhibited virulence activity in tomato plants with or without Pto. The rest of the mutations abolished the virulence. The identification of these mutants suggested that the avirulence function of AvrPto can be structurally separated from the virulence function. |
| Links |
PubMed Online version:10.1094/MPMI.2000.13.6.592 |
| Keywords |
Amino Acid Motifs; Amino Acid Substitution; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Electrophoresis, Polyacrylamide Gel; Lycopersicon esculentum/genetics; Lycopersicon esculentum/microbiology; Plant Diseases/genetics; Plant Diseases/microbiology; Plant Proteins; Point Mutation; Protein-Serine-Threonine Kinases/genetics; Pseudomonas/genetics; Pseudomonas/pathogenicity; Virulence/genetics |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0009405: pathogenesis |
ECO:0000315: |
P |
Fig. 1 (A-E). The virulence function of avrPto in the Pseudomonas syringae pv. tomato T1 strain. |
complete | ||||
See also
References
See Help:References for how to manage references in GONUTS.
