PMID:10542187

Citation	Wengelnik, K, Rossier, O and Bonas, U (1999) Mutations in the regulatory gene hrpG of Xanthomonas campestris pv. vesicatoria result in constitutive expression of all hrp genes. J. Bacteriol. 181:6828-31
Abstract	hrpG is a key regulatory gene for transcriptional activation of pathogenicity genes (hrp) of Xanthomonas campestris pv. vesicatoria. We identified three mutations in hrpG which render hrp gene expression constitutive in normally suppressing medium. The mutations in hrpG result in novel amino acid substitutions compared to mutations in related proteins, such as OmpR. In addition, mutated hrpG enhances the timing and intensity of plant reactions in infection assays.
Links	PubMed PMC94150
Keywords	Amino Acid Sequence; Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Gene Expression Regulation, Bacterial; Genes, Regulator; Molecular Sequence Data; Mutation; Plant Diseases/microbiology; Plant Leaves/microbiology; Plants, Toxic; Tobacco/microbiology; Transcription Factors; Xanthomonas campestris/genetics; Xanthomonas campestris/metabolism; Xanthomonas campestris/pathogenicity
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Annotations

Gene product	Qualifier	GO Term	Evidence Code	with/from	Aspect	Extension	Notes	Status
XANC5:Q3BW18	involved_in	GO:0010468: regulation of gene expression	ECO:0000315: mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
XANC5:Q3BW18	involved_in	GO:0009405: pathogenesis	ECO:0000314: direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
XANC5:Q3BW18		GO:0010468: regulation of gene expression	ECO:0000315:		P		Figure 1 - slight increase in promoter activity with plasmid containing HrpG, but large increase in promoter activity with plasmid containing HrpG mutant	complete CACAO 3391
XANC5:Q3BW18		GO:0009405: pathogenesis	ECO:0000314:		P		Figure 3	complete CACAO 3424

References

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