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PLAF7:Q8IL04

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Species (Taxon ID) Plasmodium falciparum (isolate 3D7). (36329)
Gene Name(s) HDP
Protein Name(s) Heme detoxification protein
External Links
UniProt Q8IL04
EMBL AE014187
RefSeq XP_001348620.1
ProteinModelPortal Q8IL04
EnsemblProtists PF14_0446:mRNA
GeneID 812028
GenomeReviews AE014187_GR
KEGG pfa:PF14_0446
EuPathDB EupathDB:PF14_0446
HOGENOM HBG628843
ProtClustDB CLSZ2431737
InterPro IPR000782
Gene3D G3DSA:2.30.180.10
Pfam PF02469
SMART SM00554
SUPFAM SSF82153
PROSITE PS50213

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004392

heme oxygenase (decyclizing) activity

PMID:18437218[1]

ECO:0000314

F

Figure 5b - immuno-fluorescence staining using an anti-HDP antibody showed that the transfected parasite continually expressed HDP, this indicated that the HDP locus was not disrupted.

complete
CACAO 4082

part_of

GO:0044164

host cell cytosol

PMID:18437218[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0042167

heme catabolic process

PMID:18437218[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

PMID:18437218[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

PMID:18437218[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:99959
PANTHER:PTN000096377
RGD:1305285
UniProtKB:Q15582

C

Seeded From UniProt

complete

involved_in

GO:0042167

heme catabolic process

PMID:18437218[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0030430

host cell cytoplasm

PMID:18437218[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0020037

heme binding

PMID:24025682[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0020020

food vacuole

PMID:18437218[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

PMID:18437218[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004392

heme oxygenase (decyclizing) activity

PMID:18437218[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004392

P

Seeded From UniProt

complete

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1035

C

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

part_of

GO:0005773

vacuole

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0926
UniProtKB-SubCell:SL-0272

C

Seeded From UniProt

complete

part_of

GO:0044164

host cell cytosol

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0384

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Jani, D et al. (2008) HDP-a novel heme detoxification protein from the malaria parasite. PLoS Pathog. 4 e1000053 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Nakatani, K et al. (2013) Heme-binding properties of heme detoxification protein from Plasmodium falciparum. Biochem. Biophys. Res. Commun. 439 477-80 PubMed GONUTS page