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PIRSE:Q9P8C9

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Species (Taxon ID) Piromyces sp. (strain E2). (73868)
Gene Name(s) xylA (ECO:0000313 with EMBL:CAB76571.1)
Protein Name(s) Xylose isomerase (ECO:0000256 with RuleBase:RU000609)
External Links
UniProt Q9P8C9
EMBL AJ249909
ProteinModelPortal Q9P8C9
SMR Q9P8C9
GO GO:0046872
GO:0009045
GO:0042732
GO:0006098
Gene3D 3.20.20.150
HAMAP MF_00455
InterPro IPR013022
IPR013452
IPR001998
Pfam PF01261
PRINTS PR00688
SUPFAM SSF51658
TIGRFAMs TIGR02630
PROSITE PS51415

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009045

xylose isomerase activity

PMID:22685138[1]

ECO:0000315

F

Table 2 depicts the wild-type xylose isomerase gene from Piromyces sp. and the first-, second-, and third-round mutants expressed in S. cerevisiae. In vitro xylose isomerase activity was measured and reported.

complete
CACAO 7150

GO:0044577

xylose catabolic process to ethanol

PMID:22685138[1]

ECO:0000315

P

Figure 3 depicts oxygen-limited fermentation tests using the xylA mutants. Ethanol production was only present in the second- and third- round mutants, and xylose consumption was increased in these strains.

complete
CACAO 7402

involved_in

GO:0044577

xylose catabolic process to ethanol

PMID:22685138[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0009045

xylose isomerase activity

PMID:22685138[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001998

P

Seeded From UniProt

complete

enables

GO:0009045

xylose isomerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001998
InterPro:IPR013452

F

Seeded From UniProt

complete

enables

GO:0009045

xylose isomerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:5.3.1.5

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0119

P

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

involved_in

GO:0042732

D-xylose metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0859

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Lee, SM et al. (2012) Directed evolution of xylose isomerase for improved xylose catabolism and fermentation in the yeast Saccharomyces cerevisiae. Appl. Environ. Microbiol. 78 5708-16 PubMed GONUTS page