PEPDI:CH60

Species (Taxon ID)	Peptoclostridium difficile (Clostridium difficile). (1496)
Gene Name(s)	groL (ECO:0000255 with HAMAP-Rule:MF_00600) (synonyms: groEL (ECO:0000255 with HAMAP-Rule:MF_00600))
Protein Name(s)	60 kDa chaperonin (ECO:0000255 with HAMAP-Rule:MF_00600) GroEL protein (ECO:0000255 with HAMAP-Rule:MF_00600) Protein Cpn60 (ECO:0000255 with HAMAP-Rule:MF_00600)
External Links
UniProt	Q9KKF0
EMBL	AF080547 AF159449
ProteinModelPortal	Q9KKF0
SMR	Q9KKF0
STRING	272563.CD0194
eggNOG	ENOG4105CJ9 COG0459
GO	GO:0005737 GO:0005524 GO:0044650 GO:0042026
Gene3D	1.10.560.10 3.50.7.10
HAMAP	MF_00600
InterPro	IPR018370 IPR001844 IPR002423 IPR027409 IPR027413
Pfam	PF00118
PRINTS	PR00298
SUPFAM	SSF52029
TIGRFAMs	TIGR02348
PROSITE	PS00296

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0044650	adhesion of symbiont to host cell	PMID:11160803	ECO:0000314			P		Figure 5 shows the adhesion of C. difficile to Vero cells in the absence and presence of anti-GroEL; adhesion decreases when anti-GroEL is present indicating that GroEL is involved in the attachment of C. difficile to cells.	complete CACAO 7979
part_of	GO:0009986	cell surface	PMID:11160803	ECO:0000314	direct assay evidence used in manual assertion		C	exists_during:(GO:0009408)	Seeded From UniProt	complete
part_of	GO:0005618	cell wall	PMID:11160803	ECO:0000314	direct assay evidence used in manual assertion		C	exists_during:(GO:0009408)	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:11160803	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:11160803	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:11160803	ECO:0000314	direct assay evidence used in manual assertion		C	exists_during:(GO:0009408)	Seeded From UniProt	complete
involved_in	GO:0042538	hyperosmotic salinity response		ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010447	response to acidic pH		ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1990641	response to iron ion starvation		ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009408	response to heat		ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0044650	adhesion of symbiont to host cell	PMID:11160803	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002423 InterPro:IPR018370	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001844 InterPro:IPR018370	C		Seeded From UniProt	complete
involved_in	GO:0006457	protein folding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018370	P		Seeded From UniProt	complete
involved_in	GO:0042026	protein refolding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001844	P		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000098153	F		Seeded From UniProt	complete
involved_in	GO:0042026	protein refolding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000098153	P		Seeded From UniProt	complete
enables	GO:0051082	unfolded protein binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000098153	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000098153	C		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
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