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PELBH:HPBD

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Species (Taxon ID) Pelagibaca bermudensis (strain JCM 13377 / KCTC 12554 / HTCC2601). (314265)
Gene Name(s) hpbD
Protein Name(s) 4-hydroxyproline betaine 2-epimerase

Hyp-B 2-epimerase (4R)-4-hydroxyproline betaine 2-epimerase

External Links
UniProt Q0FPQ4
EMBL AATQ01000017
RefSeq WP_007801489.1
PDB 2PMQ
4H2H
PDBsum 2PMQ
4H2H
ProteinModelPortal Q0FPQ4
SMR Q0FPQ4
DIP DIP-60607N
STRING 314265.R2601_01638
EnsemblBacteria EAU46159
PATRIC 28150214
eggNOG ENOG4107WEA
ENOG41107K3
EvolutionaryTrace Q0FPQ4
Proteomes UP000006230
GO GO:0000287
GO:0036361
GO:0016855
GO:0006579
Gene3D 3.20.20.120
3.30.390.10
InterPro IPR029065
IPR029017
IPR013342
IPR013341
IPR001354
PANTHER PTHR13794
Pfam PF13378
PF02746
SMART SM00922
SUPFAM SSF51604
SSF54826

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016855

racemase and epimerase activity, acting on amino acids and derivatives

PMID:24056934[1]

ECO:0000314

F

Figure 4-b shows the kinetic parameters for the epimerase activity on two different substrates. Although the kcat/Km values are only modest, the authors note that the concentrations of these substrates within the cell are usually high, resulting in a large Km value being acceptable.

complete
CACAO 10215

enables

GO:0016855

racemase and epimerase activity, acting on amino acids and derivatives

PMID:24056934[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0036361

racemase activity, acting on amino acids and derivatives

PMID:24056934[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006579

amino-acid betaine catabolic process

PMID:24056934[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:A1BBM5

P

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

PMID:24056934[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006579

amino-acid betaine catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034622

P

Seeded From UniProt

complete

enables

GO:0016855

racemase and epimerase activity, acting on amino acids and derivatives

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034622

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Zhao, S et al. (2013) Discovery of new enzymes and metabolic pathways by using structure and genome context. Nature 502 698-702 PubMed GONUTS page