GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

PASMU:GSHAB

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Pasteurella multocida (strain Pm70). (272843)
Gene Name(s) gshAB (ECO:0000255 with HAMAP-Rule:MF_00782) (synonyms: gshF (ECO:0000255 with HAMAP-Rule:MF_00782))
Protein Name(s) Glutathione biosynthesis bifunctional protein GshAB (ECO:0000255 with HAMAP-Rule:MF_00782)

Gamma-GCS-GS (ECO:0000255 with HAMAP-Rule:MF_00782) GCS-GS (ECO:0000255 with HAMAP-Rule:MF_00782) Glutamate--cysteine ligase (ECO:0000255 with HAMAP-Rule:MF_00782) Gamma-ECS (ECO:0000255 with HAMAP-Rule:MF_00782) GCS (ECO:0000255 with HAMAP-Rule:MF_00782) Gamma-glutamylcysteine synthetase (ECO:0000255 with HAMAP-Rule:MF_00782) Glutathione synthetase (ECO:0000255 with HAMAP-Rule:MF_00782) GSH synthetase (ECO:0000255 with HAMAP-Rule:MF_00782) GS (ECO:0000255 with HAMAP-Rule:MF_00782) GSH-S (ECO:0000255 with HAMAP-Rule:MF_00782) GSHase (ECO:0000255 with HAMAP-Rule:MF_00782) Glutathione synthase (ECO:0000255 with HAMAP-Rule:MF_00782)

External Links
UniProt Q9CM00
EMBL AE004439
RefSeq NP_245985.1
WP_010906990.1
PDB 3LN7
PDBsum 3LN7
ProteinModelPortal Q9CM00
STRING 272843.PM1048
EnsemblBacteria AAK03132
GeneID 1244395
KEGG pmu:PM1048
PATRIC 22871339
eggNOG COG1181
HOGENOM HOG000156471
KO K01919
OMA FNPSMYM
OrthoDB EOG6BKJ7H
BioCyc PMUL272843:GC8W-1090-MONOMER
SABIO-RK Q9CM00
UniPathway UPA00142
UPA00142
Proteomes UP000000809
GO GO:0005524
GO:0004357
GO:0004363
GO:0000287
GO:0030145
Gene3D 3.30.1490.20
3.30.470.20
HAMAP MF_00782
InterPro IPR011761
IPR013815
IPR013816
IPR007370
IPR006335
Pfam PF04262
TIGRFAMs TIGR01435
PROSITE PS50975

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

Contributes to

GO:0004357

glutamate-cysteine ligase activity

PMID:16339152[1]

ECO:0000314

F

Table 2 shows an enzyme assay used in order to demonstrate Glutamate-cysteine ligase formation from GshF

complete
CACAO 4592

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014746

F

Seeded From UniProt

complete

enables

GO:0004357

glutamate-cysteine ligase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006334
InterPro:IPR006335
InterPro:IPR007370

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003806
InterPro:IPR011761
InterPro:IPR013815

F

Seeded From UniProt

complete

involved_in

GO:0006750

glutathione biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006334
InterPro:IPR006335
InterPro:IPR007370

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003806
InterPro:IPR011761

F

Seeded From UniProt

complete

enables

GO:0004357

glutamate-cysteine ligase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:6.3.2.2

F

Seeded From UniProt

complete

enables

GO:0004363

glutathione synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:6.3.2.3

F

Seeded From UniProt

complete

enables

GO:0004357

glutamate-cysteine ligase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000100155

F

Seeded From UniProt

complete

enables

GO:0004363

glutathione synthase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000100155

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000100155

F

Seeded From UniProt

complete

involved_in

GO:0006750

glutathione biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000100155

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0016874

ligase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0436

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0511

F

Seeded From UniProt

complete

involved_in

GO:0006750

glutathione biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0317
UniPathway:UPA00142

P

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0511

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Vergauwen, B et al. (2006) Characterization of the bifunctional gamma-glutamate-cysteine ligase/glutathione synthetase (GshF) of Pasteurella multocida. J. Biol. Chem. 281 4380-94 PubMed GONUTS page