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PARDP:HPBD

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Species (Taxon ID) Paracoccus denitrificans (strain Pd 1222). (318586)
Gene Name(s) hpbD
Protein Name(s) 4-hydroxyproline betaine 2-epimerase

Hyp-B 2-epimerase (4R)-4-hydroxyproline betaine 2-epimerase

External Links
UniProt A1B198
EMBL CP000489
RefSeq WP_011747512.1
YP_914988.1
PDB 4E8G
4IZG
4J1O
PDBsum 4E8G
4IZG
4J1O
ProteinModelPortal A1B198
SMR A1B198
STRING 318586.Pden_1187
EnsemblBacteria ABL69292
GeneID 4580070
KEGG pde:Pden_1187
PATRIC 22853539
eggNOG COG4948
HOGENOM HOG000140215
OMA RRVDRIN
BioCyc PDEN318586:GCVQ-1200-MONOMER
Proteomes UP000000361
GO GO:0046872
GO:0036361
GO:0006579
Gene3D 3.20.20.120
3.30.390.10
InterPro IPR029065
IPR029017
IPR013342
IPR013341
IPR001354
PANTHER PTHR13794
Pfam PF01188
PF02746
SMART SM00922
SUPFAM SSF51604
SSF54826

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016855

racemase and epimerase activity, acting on amino acids and derivatives

PMID:24056934[1]

ECO:0000314

F

Figure 4-b shows the kinetic parameters for the epimerase activity on two different substrates. The kcat/Km values are only modest. This is because the Km values are high. The authors note in the preceding text that this is acceptable since the cellular concentrations of these compounds are high.

This GO term is not specific enough but is the best currently available term.

complete
CACAO 10216

enables

GO:0016855

racemase and epimerase activity, acting on amino acids and derivatives

PMID:24056934[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0036361

racemase activity, acting on amino acids and derivatives

PMID:24056934[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006579

amino-acid betaine catabolic process

PMID:24056934[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006579

amino-acid betaine catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034622

P

Seeded From UniProt

complete

enables

GO:0016855

racemase and epimerase activity, acting on amino acids and derivatives

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034622

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Zhao, S et al. (2013) Discovery of new enzymes and metabolic pathways by using structure and genome context. Nature 502 698-702 PubMed GONUTS page