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ORENI:I3KIU5

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Species (Taxon ID) Oreochromis niloticus (Nile tilapia) (Tilapia nilotica). (8128)
Gene Name(s) LOC100703354 (ECO:0000313 with Ensembl:ENSONIP00000021040) (synonyms: POR (ECO:0000256 with HAMAP-Rule:MF_03212))
Protein Name(s) NADPH--cytochrome P450 reductase (ECO:0000256 with HAMAP-Rule:MF_03212, ECO:0000256 with PIRNR:PIRNR000208)

CPR (ECO:0000256 with HAMAP-Rule:MF_03212) P450R (ECO:0000256 with HAMAP-Rule:MF_03212)

External Links
UniProt I3KIU5
EMBL AERX01021589
AERX01021590
RefSeq XP_003449358.1
XP_005454397.1
STRING 8128.ENSONIP00000021040
Ensembl ENSONIT00000021059
GeneID 100703354
eggNOG KOG1158
COG0369
GeneTree ENSGT00940000156847
InParanoid I3KIU5
OMA TKMDVAF
OrthoDB 318396at2759
TreeFam TF105719
Proteomes UP000005207
GO GO:0005789
GO:0016021
GO:0050660
GO:0010181
GO:0050661
GO:0003958
Gene3D 1.20.990.10
3.40.50.360
3.40.50.80
HAMAP MF_03212
InterPro IPR003097
IPR017927
IPR001094
IPR008254
IPR001709
IPR029039
IPR039261
IPR023173
IPR001433
IPR023208
IPR017938
Pfam PF00667
PF00258
PF00175
PIRSF PIRSF000208
PRINTS PR00369
PR00371
SUPFAM SSF52218
SSF52343
SSF63380
PROSITE PS51384
PS50902

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0003958

NADPH-hemoprotein reductase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.6.2.4

F

Seeded From UniProt

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

C

Seeded From UniProt

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

enables

GO:0016491

oxidoreductase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

enables

GO:0050661

NADP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

F

Seeded From UniProt

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

C

Seeded From UniProt

enables

GO:0050660

flavin adenine dinucleotide binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

F

Seeded From UniProt

enables

GO:0010181

FMN binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

F

Seeded From UniProt

enables

GO:0003958

NADPH-hemoprotein reductase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

F

Seeded From UniProt

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001094
InterPro:IPR001433
InterPro:IPR001709
InterPro:IPR003097
InterPro:IPR017927
InterPro:IPR023173
InterPro:IPR023208

P

Seeded From UniProt

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001433
InterPro:IPR001709
InterPro:IPR003097
InterPro:IPR017927
InterPro:IPR023173

F

Seeded From UniProt

enables

GO:0010181

FMN binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001094
InterPro:IPR008254

F

Seeded From UniProt

enables

GO:0003958

NADPH-hemoprotein reductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023208

F

Seeded From UniProt

enables

GO:0003958

NADPH-hemoprotein reductase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.6.2.4

F

Seeded From UniProt

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

C

Seeded From UniProt

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

enables

GO:0016491

oxidoreductase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

enables

GO:0050661

NADP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

F

Seeded From UniProt

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

C

Seeded From UniProt

enables

GO:0050660

flavin adenine dinucleotide binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

F

Seeded From UniProt

enables

GO:0010181

FMN binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

F

Seeded From UniProt

enables

GO:0003958

NADPH-hemoprotein reductase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000239476

F

Seeded From UniProt

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001094
InterPro:IPR001433
InterPro:IPR001709
InterPro:IPR003097
InterPro:IPR017927
InterPro:IPR023173
InterPro:IPR023208

P

Seeded From UniProt

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001433
InterPro:IPR001709
InterPro:IPR003097
InterPro:IPR017927
InterPro:IPR023173

F

Seeded From UniProt

enables

GO:0010181

FMN binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001094
InterPro:IPR008254

F

Seeded From UniProt

enables

GO:0003958

NADPH-hemoprotein reductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023208

F

Seeded From UniProt

GO:0015034

obsolete cytochrome P450 activity

PMID:29775944[1]

ECO:0007297

experimental evidence used in automatic assertion

F

Fig. 2. Transcriptional levels of genes of interest from Oreochromis niloticus from the four reservoirs of the Iguaçu River. A e Liver vitellogenin, B e Liver CYP1A, C e Liver CYP3A, D e Gonad CYP3A, E e Gonad aromatase, F e Brain aromatase, and G e Brain gnrh.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Yamamoto, FY et al. (2018) Alterations of cytochrome P450 and the occurrence of persistent organic pollutants in tilapia caged in the reservoirs of the Iguaçu River. Environ. Pollut. 240 670-682 PubMed GONUTS page