NEIGO:O30554

Species (Taxon ID)	Neisseria gonorrhoeae. (485)
Gene Name(s)	atlA (ECO:0000313 with EMBL:AAC45714.1)
Protein Name(s)	AtlA (ECO:0000313 with EMBL:AAK77140.1) Autolysin A (ECO:0000313 with EMBL:AAC45714.1)
External Links
UniProt	O30554
EMBL	AF010308 AF374415 AY803022
RefSeq	WP_003695255.1
STRING	528354.NGFG_00979
CAZy	GH104
TCDB	3.A.7.11.1
eggNOG	ENOG4108T14 COG4678
InterPro	IPR023346
SUPFAM	SSF53955

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0008933	lytic transglycosylase activity	PMID:17526702	ECO:0000314			F		Figure 2 HPLC Analysis to compare Atla-generated PG monomers, PG monomoers generated by hen egg white lysozyme and 1,6-anhydro PG monomers released by growing gonococci. PG monomers liberated by AtlA activity consisted primarily of 1,6-anhydro disaccharide tetrapeptide PG monomers, and a small portion of the released monomers consisted of the 1,6-anhydro disaccharide tripeptide. These data demonstrate that AtlA functions as a lytic transglycosylase.	complete CACAO 12175
enables	GO:0003796	lysozyme activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR034691	F		Seeded From UniProt	complete
involved_in	GO:0009253	peptidoglycan catabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR034691	P		Seeded From UniProt	complete
involved_in	GO:0019076	viral release from host cell	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR034691	P		Seeded From UniProt	complete
involved_in	GO:0044659	cytolysis by virus of host cell	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR034691	P		Seeded From UniProt	complete
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References

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