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MYCTU:RPSC

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Species (Taxon ID) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332)
Gene Name(s) sigC
Protein Name(s) ECF RNA polymerase sigma factor SigC

ECF sigma factor SigC Alternative RNA polymerase sigma factor SigC RNA polymerase sigma-C factor Sigma-C factor

External Links
UniProt P9WGH1
EMBL AL123456
PIR H70764
RefSeq NP_216585.1
YP_006515482.1
PDB 2O7G
2O8X
PDBsum 2O7G
2O8X
ProteinModelPortal P9WGH1
SMR P9WGH1
GeneID 13316873
888723
KEGG mtu:Rv2069
mtv:RVBD_2069
TubercuList Rv2069
KO K03088
OMA HIRHLQA
PhylomeDB P9WGH1
Proteomes UP000001584
GO GO:0003677
GO:0003700
GO:0016987
GO:0006352
GO:0009405
GO:0006355
GO:0009408
GO:0001666
GO:0009415
GO:0009410
Gene3D 1.10.10.10
InterPro IPR014284
IPR000838
IPR007627
IPR013249
IPR013325
IPR013324
IPR011991
Pfam PF04542
PF08281
SUPFAM SSF88659
SSF88946
TIGRFAMs TIGR02937
PROSITE PS01063

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0009415

response to water

PMID:10027986[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009410

response to xenobiotic stimulus

PMID:10027986[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009408

response to heat

PMID:10027986[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001666

response to hypoxia

PMID:10027986[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

PMID:15049808[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:15049808[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000142

regulation of DNA-templated transcription, initiation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016987

P

Seeded From UniProt

complete

involved_in

GO:2000142

regulation of DNA-templated transcription, initiation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016987

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000838
InterPro:IPR013249

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000838
InterPro:IPR007627
InterPro:IPR013249
InterPro:IPR013325
InterPro:IPR014284

F

Seeded From UniProt

complete

involved_in

GO:0006352

DNA-templated transcription, initiation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000838
InterPro:IPR007627
InterPro:IPR013249
InterPro:IPR013325
InterPro:IPR014284

P

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000838
InterPro:IPR007627
InterPro:IPR013249
InterPro:IPR013325
InterPro:IPR014284

P

Seeded From UniProt

complete

enables

GO:0016987

sigma factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000838
InterPro:IPR013249

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0731

P

Seeded From UniProt

complete

enables

GO:0016987

sigma factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0731

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Manganelli, R et al. (1999) Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis. Mol. Microbiol. 31 715-24 PubMed GONUTS page
  2. 2.0 2.1 Sun, R et al. (2004) Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 52 25-38 PubMed GONUTS page