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MYCTU:RPFE

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Species (Taxon ID) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332)
Gene Name(s) rpfE
Protein Name(s) Resuscitation-promoting factor RpfE
External Links
UniProt O53177
EMBL AL123456
PIR A70864
RefSeq NP_216966.1
PDB 4CGE
PDBsum 4CGE
ProteinModelPortal O53177
SMR O53177
STRING 83332.Rv2450c
EnsemblBacteria CCP45243
GeneID 885760
KEGG mtu:Rv2450c
PATRIC 18154045
TubercuList Rv2450c
HOGENOM HOG000051338
OMA AMIAPVD
OrthoDB EOG6N0HR0
BioCyc MTBRV:RV2450C-MONOMER
Proteomes UP000001584
GO GO:0005576
GO:0016787
GO:0010629
GO:0009405
GO:0010628
GO:0040010
InterPro IPR023346
IPR010618
Pfam PF06737
SUPFAM SSF53955

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010628

positive regulation of gene expression

PMID:23554726[1]

ECO:0000314

P

Figure 1 shows transfer of gene to E. Coli. This E. coli was then added to the GI tract of mice in order to see its effect on immune response.

complete
CACAO 8747

involved_in

GO:0040010

positive regulation of growth rate

PMID:12410821[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010629

negative regulation of gene expression

PMID:15207486[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:15207486[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

PMID:17443846[4]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

PMID:12410821[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Xue, Y et al. (2012) Expression, purification and characterization of Mycobacterium tuberculosis RpfE protein. J Biomed Res 26 17-23 PubMed GONUTS page
  2. 2.0 2.1 Mukamolova, GV et al. (2002) A family of autocrine growth factors in Mycobacterium tuberculosis. Mol. Microbiol. 46 623-35 PubMed GONUTS page
  3. 3.0 3.1 Downing, KJ et al. (2004) Global expression profiling of strains harbouring null mutations reveals that the five rpf-like genes of Mycobacterium tuberculosis show functional redundancy. Tuberculosis (Edinb) 84 167-79 PubMed GONUTS page
  4. Målen, H et al. (2007) Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. Proteomics 7 1702-18 PubMed GONUTS page